Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of the VirB4-VirB8-VirB5-VirB2 pilus assembly sequence of type IV secretion systems.

The Journal of biological chemistry - 15 Jul 2005

Yuan Qing, Carle Anna, Gao Chan, Sivanesan Durga, Aly Khaled Ahmed, Höppner Christoph, Krall Lilian, Domke Natalie, Baron Christian

Abstract excerpt

Type IV secretion systems mediate the translocation of virulence factors (proteins and/or DNA) from Gram-negative bacteria into eukaryotic cells. A complex of 11 conserved proteins (VirB1-VirB11) spans the inner and the outer membrane and assembles extracellular T-pili in Agrobacterium tumefaciens. Here we report a sequence of protein interactions required for the formation of complexes between VirB2 and VirB5,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agrobacterium tumefaciens
Share to Chromatography, Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cross-Linking Reagents

Share to Detergents

Share to Fimbriae, Bacterial

Share to Microscopy, Electron, Transmission

Share to Two-Hybrid System Techniques

Share to Virulence Factors

Source

Identifiers

PMID: 15901731
DOI: 10.1074/jbc.M502347200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the VirB4-VirB8-VirB5-VirB2 pilus assembly sequence of type IV secretion systems.PMID 15901731Read ↗

A putative transmembrane leucine zipper of agrobacterium VirB10 is essential for t-pilus biogenesis but not type IV secretion.Semantic proximity Read ↗

Agrobacterium tumefaciens VirB6 protein participates in formation of VirB7 and VirB9 complexes required for type IV secretion.Semantic proximity Read ↗

The dimer interface of Agrobacterium tumefaciens VirB8 is important for type IV secretion system function, stability, and association of VirB2 with the core complex.Semantic proximity Read ↗

Molecular characterization of the Agrobacterium tumefaciens DNA transfer protein VirB6.Semantic proximity Read ↗

Energetic components VirD4, VirB11 and VirB4 mediate early DNA transfer reactions required for bacterial type IV secretion.Semantic proximity Read ↗

Role of Agrobacterium VirB11 ATPase in T-pilus assembly and substrate selection.Semantic proximity Read ↗

Biogenesis of T pili in Agrobacterium tumefaciens requires precise VirB2 propilin cleavage and cyclization.Semantic proximity Read ↗

Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity.Semantic proximity Read ↗

Agrobacterium type IV secretion is a two-step process in which export substrates associate with the virulence protein VirJ in the periplasm.Semantic proximity Read ↗

Evidence for VirB4-mediated dislocation of membrane-integrated VirB2 pilin during biogenesis of the Agrobacterium VirB/VirD4 type IV secretion system.Semantic proximity Read ↗

A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis.Semantic proximity Read ↗

Pili are essential for conjugation also in many Gram-positive bacteriaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.