Article
Following autolysis in proteases by NMR: insights into multiple unfolding pathways and mutational plasticities.
Biophysical chemistry - 20 Aug 2006
Chatterjee Amarnath, Hosur Ramakrishna V
Abstract excerpt
Biophysical studies in proteases are severely hampered due to the auto-cleavage property of these enzymes. In this context, we develop here a kinetic model and an NMR-based strategy to use this very autolytic property to derive useful insights into multiple unfolding pathways and mutational plast...
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