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Article

Do proteins with similar folds have similar transition state structures? A diffuse transition state of the 169 residue apoflavodoxin.

Journal of molecular biology - 9 Jun 2006

Bueno Marta, Ayuso-Tejedor Sara, Sancho Javier

Abstract excerpt

Apoflavodoxin from Anabaena PCC 7119 is a 169 residue globular protein of known structure and energetics. Here, we present a comprehensive Phi-value analysis to characterize the structure of its transition state. A total of 34 non-disruptive mutations are made throughout the structure and a range of Phi-values from zero to one are observed. In addition, a small set of eight aliphatic small-to-large mutations have...

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Identifiers

PMID: 16647718
DOI: 10.1016/j.jmb.2006.03.067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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