Article
The carcinogenic role of oncogenic HPV and p53 gene mutation in cervical adenocarcinomas.
Medical oncology (Northwood, London, England) - 1 Jan 2006
Andersson S, Hellström A-C, Ren Zhi-Ping, Wilander E
Abstract excerpt
Thirty tumors were collected from our archive of cervical adenocarcinomas. They were examined with respect to the content of oncogenic HPV and presence of mutations in the p53 gene exons 5 through 8. Furthermore, available clinical information on the cases was reviewed. For the detection of p53 gene and presence of oncogenic HPV, PCR followed by direct sequence analysis of the amplified DNA was employed....
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