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Article

Role of TP53 mutations in vulvar carcinomas.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Sept 2011

Choschzick Matthias, Hantaredja Widianto, Tennstedt Pierre, Gieseking Frederike, Wölber Linn, Simon Ronald

Abstract excerpt

Human papillomavirus (HPV)-independent development of vulvar carcinomas is common and the disruption of the TP53 pathway seems to play a key role in these tumors. Overexpression of TP53 in precursor lesions (differentiated VIN) and associated invasive carcinomas is regarded as an important diagnostic feature of this subtype of vulvar cancer. To determine the relationship of TP53 mutation status with...

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Source

Identifiers

PMID: 21804386
DOI: 10.1097/PGP.0b013e3182184c7a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of TP53 mutations in vulvar carcinomas.PMID 21804386Read ↗

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Squamous Precursor Lesions of the Vulva: A Practical Approach.Semantic proximity Read ↗

p53 and p16 expression profiles in vulvar cancer: a translational analysis by the Arbeitsgemeinschaft Gynäkologische Onkologie Chemo and Radiotherapy in Epithelial Vulvar Cancer study group.Semantic proximity Read ↗

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Molecular Subtypes of Vulvar Squamous Cell Carcinoma: the significance of HPV-independent/p53 Wild TypeSemantic proximity Read ↗

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