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Article

CYP2D6 genotype and venlafaxine-XR concentrations in depressed elderly.

International journal of geriatric psychiatry - 1 Jun 2006

Whyte Ellen M, Romkes Marjorie, Mulsant Benoit H, Kirshne Margaret A, Begley Amy E, Reynolds Charles F, Pollock Bruce G

Abstract excerpt

INTRODUCTION: The elderly are at increased risk for medication-related adverse events. Recent reports indicate that venlafaxine may put the elderly at increased risk of cardio- and cerebrovascular adverse events. We investigated the relationship between the CYP2D6 polymorphism and steady-state plasma concentration of venlafaxine (VEN) and its primary metabolite o-desmethylvenlafaxine (ODV) in elderly participants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16642541
DOI: 10.1002/gps.1522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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