Article
Cytochrome P450 2D6 genotype variation and venlafaxine dosage.
Mayo Clinic proceedings - 1 Sept 2007
McAlpine Donald E, O'Kane Dennis J, Black John L, Mrazek David A
Abstract excerpt
OBJECTIVE: To determine whether the presence or absence of a fully functioning cytochrome P450 2D6 allele was associated with the dosage of the antidepressant drug venlafaxine in patients who had either adverse effects or absence of a therapeutic response to treatment with the immediate release or extended release form of venlafaxine. PATIENTS AND METHODS: We reviewed the electronic medical records of 199...
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