Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant human immunodeficiency virus type 1 genomes with defects in RNA dimerization or encapsidation.

Journal of virology - 1 May 1997

Clever J L, Parslow T G

Abstract excerpt

Retrovirus particles each contain two copies of the viral genome in the form of a noncovalently linked RNA dimer. Earlier studies have mapped a cis-acting region near the 5' end of the human immunodeficiency virus type 1 (HIV-1) genome, termed the psi locus, which appears essential for initiation of genomic dimerization, as well as for interactions with the HIV-1 Gag protein that are thought to target the RNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Genome, Viral
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to RNA, Viral

Share to Virus Assembly

Source

Open in PubMed Open full text

Identifiers

PMID: 9094610
DOI: 10.1128/JVI.71.5.3407-3414.1997
PMCID: PMC191485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant human immunodeficiency virus type 1 genomes with defects in RNA dimerization or encapsidation.PMID 9094610Read ↗

Sequences Downstream of the 5′ Splice Donor Site Are Required for both Packaging and Dimerization of Human Immunodeficiency Virus Type 1 RNASemantic proximity Read ↗

Duplication of the primary encapsidation and dimer linkage region of human immunodeficiency virus type 1 RNA results in the appearance of monomeric RNA in virions.Semantic proximity Read ↗

HIV-2 genome dimerization is required for the correct processing of Gag: a second-site reversion in matrix can restore both processes in dimerization-impaired mutant viruses.Semantic proximity Read ↗

A dual role of the putative RNA dimerization initiation site of human immunodeficiency virus type 1 in genomic RNA packaging and proviral DNA synthesisSemantic proximity Read ↗

The human immunodeficiency virus type 1 encapsidation site is a multipartite RNA element composed of functional hairpin structuresSemantic proximity Read ↗

Role of the DIS hairpin in replication of human immunodeficiency virus type 1.Semantic proximity Read ↗

Dissociation of Genome Dimerization from Packaging Functions and Virion Maturation of Human Immunodeficiency Virus Type 1Semantic proximity Read ↗

Functional Analysis of the Core Human Immunodeficiency Virus Type 1 Packaging Signal in a Permissive Cell LineSemantic proximity Read ↗

Conserved determinants of lentiviral genome dimerization.Semantic proximity Read ↗

Compensatory Point Mutations in the Human Immunodeficiency Virus Type 1 Gag Region That Are Distal from Deletion Mutations in the Dimerization Initiation Site Can Restore Viral ReplicationSemantic proximity Read ↗

An extended stem-loop 1 is necessary for human immunodeficiency virus type 2 replication and affects genomic RNA encapsidation.Semantic proximity Read ↗

Deficient dimerization of human immunodeficiency virus type 1 RNA caused by mutations of the u5 RNA sequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.