Article
Molecular mechanisms of simian immunodeficiency virus SIV(agm) RNA encapsidation.
Virology - 20 Jun 2007
Fu William, Prasad V V S P, Chen Jianbo, Nikolaitchik Olga, Hu Wei-Shau
Abstract excerpt
Primate lentiviruses are composed of several distinct lineages, including human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVagm. HIV-1 and HIV-2 have significant differences in the mechanisms of viral RNA encapsidation. Therefore, the RNA packaging mechanisms of SIVagm cannot be predicted from the studies of HIV-1 and HIV-2. We examined the roles of the nucleocapsid (NC)...
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