Article
Analysis of IL1B, TAP1, TAP2 and IKBL polymorphisms on susceptibility to tuberculosis.
Tissue antigens - 1 Apr 2006
Gomez L M, Camargo J F, Castiblanco J, Ruiz-Narváez E A, Cadena J, Anaya J M
Abstract excerpt
Genetic determinants of human susceptibility to tuberculosis (TB) have not been completely elucidated. Interleukin-1 beta (IL-1beta) and the inhibitor of kB-like (IkBL) are important molecules that participate in the inflammatory response required for the immunological control of a broad spectrum of infectious agents. The transporter associated with antigen processing (TAP) is involved in the antigen processing...
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