Article
Human toll-like receptor 1 T1805G polymorphism and susceptibility to pulmonary tuberculosis in northern Spain.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 May 2013
Ocejo-Vinyals J G, Puente de Mateo E, Ausín F, Agüero R, Arroyo J L, Gutiérrez-Cuadra M, Fariñas M C
Abstract excerpt
Toll-like receptors (TLRs) are key sensors of mycobacterial infections and play a crucial role in the initiation and coordination of the antimycobacterial innate immune response. T1805G, a functional TLR1 single nucleotide polymorphism (SNP), has been associated with susceptibility to pulmonary tuberculosis (PTB), but contradictory results among different populations have been reported. Our objective was to study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.