Article
Lack of an association between interleukin-12 receptor beta1 polymorphisms and tuberculosis in Koreans.
Respiration; international review of thoracic diseases - 1 Jan 2000
Lee Hye Won, Lee Hee Seok, Kim Deog Kyeom, Ko Dong Seok, Han Sung Koo, Shim Young-Soo, Yim Jae-Joon
Abstract excerpt
BACKGROUND: The fact that only 10% of people infected with Mycobacterium tuberculosis develop clinical tuberculosis (TB) suggests the presence of genetic factors in the pathogenesis of TB. To date, a number of single nucleotide polymorphisms (SNPs) in several candidate genes have been proposed as genetic risk factors of TB; however, reports are conflicting. OBJECTIVES: We investigated whether SNPs in the...
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