Association of TAP1 1177A>G and 2090A>G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study.

doi:10.1590/S1678-9946202163055

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Article

Association of TAP1 1177A>G and 2090A>G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study.

Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2021

Cazarez-Navarro Gerardo, Palomares-Marín Jaime, Rodríguez-Preciado Sergio Yair, Pereira-Suárez Ana Laura, Martínez-López Erika, Bacilio-Medrano Eva Adriana, Huerta-Olvera Selene, Hernández-Cañaveral Iván Isidro

Abstract excerpt

Latent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen...

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PMID: 34231820
DOI: 10.1590/S1678-9946202163055
PMCID: PMC8266304

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