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Article

Filamin C in cardiomyopathy: from physiological roles to DNA variants.

Heart failure reviews - 1 Jul 2022

Song Shen, Shi Anteng, Lian Hong, Hu Shengshou, Nie Yu

Abstract excerpt

Cardiomyopathy affects approximately 1 in 500 adults and is the leading cause of death. Familial cases are common, and mutations in many genes are involved in cardiomyopathy, especially those in genes encoding cytoskeletal, sarcomere, and nuclear envelope proteins. Filamin C is an actin-binding protein encoded by filamin C (FLNC) gene and participates in sarcomere stability maintenance. FLNC was first...

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PMID: 34535832
DOI: 10.1007/s10741-021-10172-z

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Filamin C in cardiomyopathy: from physiological roles to DNA variants.PMID 34535832Read ↗

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