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Article

Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo.

Molecular cell - 21 Apr 2006

Pavan Kumar P, Purbey Prabhat Kumar, Sinha Chandan Kumar, Notani Dimple, Limaye Amita, Jayani Ranveer S, Galande Sanjeev

Abstract excerpt

SATB1 regulates gene expression by acting as a "docking site" for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters. However, how these contrasting effectors act at the level of SATB1 is not clear. We show here that phosp...

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Source

Identifiers

PMID: 16630892
DOI: 10.1016/j.molcel.2006.03.010

Genes

SATB1
HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16630892-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo.PMID 16630892Read ↗

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