Article
A nuclear targeting determinant for SATB1, a genome organizer in the T cell lineage.
Cell cycle (Georgetown, Tex.) - 1 Aug 2005
Nakayama Yuji, Mian I Saira, Kohwi-Shigematsu Terumi, Ogawa Takuya
Abstract excerpt
SATB1 is a nuclear protein, which acts as a cell-type specific genome organizer and gene regulator essential for T cell differentiation and activation. Several functional domains of SATB1 have been identified. However, the region required for nuclear localization remains unknown. To delineate this region, we employed sequence analysis to identify phylogenetically diverse members of the SATB1 protein family, and...
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