Article
Opaque cells signal white cells to form biofilms in Candida albicans.
The EMBO journal - 17 May 2006
Daniels Karla J, Srikantha Thyagarajan, Lockhart Shawn R, Pujol Claude, Soll David R
Abstract excerpt
Upon homozygosis from a/alpha to a/a or alpha/alpha, Candida albicans must still switch from the 'white' to 'opaque' phenotype to mate. It was, therefore, surprising to discover that pheromone selectively upregulated mating-associated genes in mating-incompetent white cells without causing G1 arrest or shmoo formation. White cells, like opaque cells, possess pheromone receptors, although their distribution and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
