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Article

Mice lacking inducible nitric oxide synthase develop spontaneous hypercholesterolaemia and aortic atheromas.

Atherosclerosis - 1 May 2001

Ihrig M, Dangler C A, Fox J G

Abstract excerpt

Nitric oxide (NO) has been implicated in various aspects of the atherogenic process and has been shown to possess both protective and cytotoxic properties. Recently, increased expression of inducible nitric oxide synthase (iNOS) has been detected in atherosclerotic lesions, although there is no consensus as to its pathogenetic significance [1,2]. In this longitudinal study we show that iNOS plays an important...

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PMID: 11369002
DOI: 10.1016/s0021-9150(00)00636-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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