Article
Scanning the HIV genome for CD4+ T cell epitopes restricted to HLA-DP4, the most prevalent HLA class II molecule.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 2006
Cohen William M, Pouvelle-Moratille Sandra, Wang Xiao-Fei, Farci Sandrine, Munier Gaetan, Charron Dominique, Ménez André, Busson Marc, Maillère Bernard
Abstract excerpt
HLA-DP4 alleles are carried by 75% of individuals and are the most frequent HLA II alleles worldwide. Because we have recently characterized the peptide-binding specificity of HLA-DP4 molecules, we developed a peptide-binding prediction method to identify HLA-DP4-restricted peptides in multiple A...
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