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Article

Functional annotation of mouse mutations in embryonic stem cells by use of expression profiling.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2004

Symula Derek J, Zhu Yiwen, Schimenti John C, Rubin Edward M

Abstract excerpt

Expression profiling offers a potential high-throughput phenotype screen for mutant mouse embryonic stem (ES) cells. We have assessed the ability of expression arrays to distinguish among heterozygous mutant ES cell lines and to accurately reflect the normal function of the mutated genes. Two ES...

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PMID: 14727137
DOI: 10.1007/s00335-002-2228-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14727137-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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