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Article

Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma.

Carcinogenesis - 1 Sept 2006

Li Chunying, Liu Zhensheng, Wang Li-E, Strom Sara S, Lee Jeffrey E, Gershenwald Jeffrey E, Ross Merrick I, Mansfield Paul F, Cormier Janice N, Prieto Victor G, Duvic Madeleine, Grimm Elizabeth A, Wei Qingyi

Abstract excerpt

Sunlight causes various kinds of DNA damage, including oxidative lesions that are removed effectively by the base excision repair (BER) pathway, in which ADPRT, XRCC1 and APE1 play a key role. However, genetic variation in these genes may alter their functions. We hypothesized that ADPRT, XRCC1 and APE1 polymorphisms are associated with risk of cutaneous melanoma (CM). In a hospital-based case-control study of...

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Identifiers

PMID: 16621887
DOI: 10.1093/carcin/bgl042

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XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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