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Article

Genetic variants of the APE1 gene and the risk of vitiligo in a Chinese population: a genotype-phenotype correlation study.

Free radical biology & medicine - 1 May 2013

Wei Chao, Jian Zhe, Wang Lin, Qiang Huini, Shi Qiong, Guo Sen, Li Kai, Huang Ye, Liu Ling, Li Qiang, Luan Qi, Yi Xiuli, Li Xia, Wang Gang, Gao Tianwen, Li Chunying

Abstract excerpt

Vitiligo is an acquired depigmentation disorder, and reactive oxygen species play an important role in melanocyte damage. Base excision repair is the major pathway responsible for removing reactive oxygen species-induced DNA damage, in which APE1, ADPRT, and XRCC1 play key roles. To investigate the association between genetic variations of these genes and the risk of vitiligo in Chinese populations, we genotyped...

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Identifiers

PMID: 23369758
DOI: 10.1016/j.freeradbiomed.2013.01.009

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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