Article
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size.
BMC bioinformatics - 18 Apr 2006
Allen-Brady Kristina, Wong Jathine, Camp Nicola J
Abstract excerpt
BACKGROUND: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and independent individuals to be analyzed together, to test genetic markers and qualitative or quantitative traits. Our software, PedGenie, uses Monte Carlo significance testing to provide a valid test for related individuals that can be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
