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Article

Association of transforming growth factor-beta 1 functional polymorphisms with natural clearance of hepatitis C virus.

The Journal of infectious diseases - 15 May 2006

Kimura Tomomi, Saito Takafumi, Yoshimura Mika, Yixuan Song, Baba Masanori, Ji Guijin, Muramatsu Masaaki, Kawata Sumio

Abstract excerpt

Transforming growth factor (TGF)-beta 1 suppresses the proliferation and cytotoxicity of natural killer (NK) cells, which play critical roles in resolving hepatitis C virus (HCV) infection, especially during the acute phase. We examined 230 anti-HCV antibody-positive subjects for HCV RNA and the -509T/C genotype in the TGF-beta 1 gene promoter. The -509CC genotype and the -509C allele were significantly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16619184
DOI: 10.1086/503436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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