Article
Clearance of hepatitis C virus is not associated with single nucleotide polymorphisms in the IL-1, -6, or -10 genes.
Human immunology - 1 Feb 2005
Minton Elizabeth J, Smillie David, Smith Paula, Shipley Suzanne, McKendrick Michael W, Gleeson Dermot C, Underwood James C E, Cannings Christopher, Wilson Anthony G
Abstract excerpt
Hepatitis C virus (HCV) commonly causes a chronic infection, but a minority of patients are able to clear the virus and do not run the risk of developing HCV-induced organ damage. Genetic associations between immunoregulatory cytokines interleukin (IL)-1, -6, and -10 with clinical features of HCV, including virus clearance, have been inconsistent. We determined cytokine genotypes in 606 patients who had serologic...
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