Article
Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection.
European journal of gastroenterology & hepatology - 1 Sept 2006
Wietzke-Braun Perdita, Maouzi Adil B, Mänhardt Larissa B, Bickeböller Heike, Ramadori Giuliano, Mihm Sabine
Abstract excerpt
OBJECTIVE: Interferon-alpha (IFN-alpha), an important mediator for the host's innate antiviral defense system, has been approved for the treatment of persistent viral infections. We investigated whether two functional polymorphisms in genes involved in IFN-alpha signaling and effector functions a...
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