Article
Expression of constitutively active angiotensin receptors in the rostral ventrolateral medulla increases blood pressure.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2006
Allen Andrew M, Dosanjh Jaspreet K, Erac Marco, Dassanayake Sashikala, Hannan Ross D, Thomas Walter G
Abstract excerpt
Angiotensin type 1A (AT(1A)) receptors are expressed within the rostral ventrolateral medulla, and microinjections of angiotensin II into this region increase sympathetic vasomotor tone. To determine the effect of sustained increases in AT(1A) receptor density or activity in rostral ventrolateral medulla, we used radiotelemetry to monitor blood pressure in conscious rats before and after bilateral microinjection...
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