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Article

The folding pathway of spectrin R17 from experiment and simulation: using experimentally validated MD simulations to characterize States hinted at by experiment.

Journal of molecular biology - 26 May 2006

Scott Kathryn A, Randles Lucy G, Moran Stephen J, Daggett Valerie, Clarke Jane

Abstract excerpt

We present an experimental and computational analysis of the folding pathway of the 17th domain of chicken brain alpha-spectrin, R17. Wild-type R17 folds in a two-state manner and the chevron plot (plot of the logarithm of the observed rate constant against concentration of urea) shows essentiall...

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Identifiers

PMID: 16618492
DOI: 10.1016/j.jmb.2006.03.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16618492-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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