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Article

Testing protein-folding simulations by experiment: B domain of protein A.

Proceedings of the National Academy of Sciences of the United States of America - 4 May 2004

Sato Satoshi, Religa Tomasz L, Daggett Valerie, Fersht Alan R

Abstract excerpt

We have assessed the published predictions of the pathway of folding of the B domain of protein A, the pathway most studied by computer simulation. We analyzed the transition state for folding of the three-helix bundle protein, by using experimental Phi values on some 70 suitable mutants. Surpris...

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Identifiers

PMID: 15069202
DOI: 10.1073/pnas.0401396101
PMCID: PMC406447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15069202-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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