Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Affinity, kinetic, and structural study of the interaction of 3-O-sulfotransferase isoform 1 with heparan sulfate.

Biochemistry - 25 Apr 2006

Muñoz Eva, Xu Ding, Kemp Melissa, Zhang Fuming, Liu Jian, Linhardt Robert J

Abstract excerpt

The 3-O-sulfonation of glucosamine residues in heparan sulfate (HS) by 3-O-sulfotransferase (3-OST) is a key substitution that is present in HS sequences of biological importance, in particular HS anticoagulant activity. Six different isoforms of 3-OST have been identified that exhibit different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Crystallography, X-Ray
Share to Heparitin Sulfate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoenzymes

Share to Kinetics

Share to Substrate Specificity

Share to Sulfotransferases

Share to Surface Plasmon Resonance

Source

Open in PubMed Open full text

Identifiers

PMID: 16618101
DOI: 10.1021/bi052403n
PMCID: PMC4129659

Genes

SPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16618101-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Affinity, kinetic, and structural study of the interaction of 3-O-sulfotransferase isoform 1 with heparan sulfate.PMID 16618101Read ↗

Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1.Semantic proximity Read ↗

Heparan sulfate proteoglycans.Semantic proximity Read ↗

Heparan sulphate N-sulphotransferase activity: reaction mechanism and substrate recognition.Semantic proximity Read ↗

Role of the carboxyl-terminal region in the activity of N-acetylglucosamine 6-o-sulfotransferase-1.Semantic proximity Read ↗

A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation.Semantic proximity Read ↗

Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia.Semantic proximity Read ↗

[Molecular diversity and biological functions of proteoglycan sulfotransferase].Semantic proximity Read ↗

The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation.Semantic proximity Read ↗

The molecular basis for the broad substrate specificity of human sulfotransferase 1A1.Semantic proximity Read ↗

A High-Throughput SPR-Based Array for Quantitative Profiling of Glycosaminoglycan–Protein InteractionsSemantic proximity Read ↗

Biology and function of the reversible sulfation pathway catalysed by human sulfotransferases and sulfatasesSemantic proximity Read ↗

Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.