Article
Arachidonic acid is a chemoattractant for Dictyostelium discoideum cells.
Journal of biosciences - 1 Dec 2007
Schaloske Ralph H, Blaesius Dagmar, Schlatterer Christina, Lusche Daniel F
Abstract excerpt
Cyclic AMP (cAMP)is a natural chemoattractant of the social amoeba Dictyostelium discoideum. It is detected by cell surface cAMP receptors. Besides a signalling cascade involving phosphatidylinositol 3,4,5-trisphosphate (PIP3), Ca2+ signalling has been shown to have a major role in chemotaxis. Previously, we have shown that arachidonic acid (AA) induces an increase in the cytosolic Ca2+ concentration by causing...
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