Prostate cancer cells use genetic and epigenetic mechanisms for progression to androgen independence.

Abstract excerpt

Studies on the genetic basis of prostate cancer (PCa) have lead to mixed results with the only consensus being that PCa is a complex disease. Our goal was to gain insight into potential events involved in the acquisition of the androgen-refractory phenotype in PCa cells regardless of DNA-change dependence. To this end, we examined two LNCaP PCa cell line models of progression-one developed in vivo and one...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Androgens
• Share to Chromosome Banding