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Article

Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current.

Molecular pharmacology - 1 Jul 2006

Susankova Klara, Tousova Karolina, Vyklicky Ladislav, Teisinger Jan, Vlachova Viktorie

Abstract excerpt

We have previously reported that the reducing agent dithiothreitol (DTT) strongly increases thermally induced activity of the transient receptor potential vanilloid receptor-1 (TRPV1) channel. Here, we show that exposure to oxidizing agents also enhances the heat-induced activation of TRPV1. The actions of sulfhydryl modifiers on heat-evoked whole-cell membrane currents were examined in TRPV1-transfected human...

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Source

Identifiers

PMID: 16614139
DOI: 10.1124/mol.106.023069

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current.PMID 16614139Read ↗

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