Article
Metal oxyanion stabilization of the rat glucocorticoid receptor is independent of thiols.
The Journal of biological chemistry - 14 Oct 1994
Modarress K J, Cavanaugh A H, Chakraborti P K, Simons S S
Abstract excerpt
The ability of sodium molybdate, both to stabilize the steroid binding activity of glucocorticoid receptors and to prevent the activation of receptor-steroid complexes to a DNA binding species, has long been thought to involve thiols. Two receptor thiols in particular, Cys-656 and Cys-661 of rat receptors, have been suspected. The requirements for the action of molybdate, as well as two other metal oxyanions...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.