Article
Metal oxyanion stabilization of the rat glucocorticoid receptor is independent of thiols.
The Journal of biological chemistry - 14 Oct 1994
Modarress K J, Cavanaugh A H, Chakraborti P K, Simons S S
Abstract excerpt
The ability of sodium molybdate, both to stabilize the steroid binding activity of glucocorticoid receptors and to prevent the activation of receptor-steroid complexes to a DNA binding species, has long been thought to involve thiols. Two receptor thiols in particular, Cys-656 and Cys-661 of rat...
Topics
- Affinity Labels
- Animals
- Anions
- Base Sequence
- Cyclic GMP
- Cysteine
- Dexamethasone
- Methyl Methanesulfonate
- Molecular Sequence Data
- Molybdenum
- Mutation
- Peptide Fragments