Article
The role of interindividual variation in human carcinogenesis.
The Journal of nutrition - 1 Feb 1999
Lai C, Shields P G
Abstract excerpt
The process of chemical carcinogenesis is a complex multistage process initiated by DNA damage in growth control genes. Carcinogens enter the body from a variety of sources, but most require metabolic activation before they can damage DNA. There are multiple protective processes that include detoxification and conjugation, DNA repair and programmed cell death. Most of these functions exhibit wide interindividual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.