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Different Modes of Human Papillomavirus DNA Replication during Maintenance

12 Apr 2006

Abstract excerpt

Human papillomavirus (HPV) begins its life cycle by infecting the basal cells of the epithelium. Within these proliferating cells, the viral genomes are replicated, maintained, and passed on to the daughter cells. Using HPV episome-containing cell lines that were derived from naturally infected cervical tissues, we investigated the mode by which the viral DNAs replicate in these cells. We observed that, whereas...

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PMID: 16611903
DOI: 10.1128/jvi.80.9.4431-4439.2006

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