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Human Papillomavirus Type 16 E1 <sup>∧</sup> E4 Contributes to Multiple Facets of the Papillomavirus Life Cycle

27 Sept 2005

Abstract excerpt

The life cycle of human papillomaviruses (HPVs) is tightly linked to the differentiation program of the host's stratified epithelia that it infects. E1(circumflex)E4 is a viral protein that has been ascribed multiple biochemical properties of potential biological relevance to the viral life cycle. To identify the role(s) of the viral E1(circumflex)E4 protein in the HPV life cycle, we characterized the properties...

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PMID: 16189016
DOI: 10.1128/jvi.79.20.13150-13165.2005

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