Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combination Analysis of Hypermethylated Wnt-Antagonist Family Genes as a Novel Epigenetic Biomarker Panel for Bladder Cancer Detection

1 Apr 2006

Abstract excerpt

PURPOSE: Aberrant promoter hypermethylation of Wnt-antagonist genes contributes to the pathogenesis of several cancers. We hypothesized that combined methylation analysis of Wnt-antagonist genes could improve their use as a panel of biomarkers for diagnosing and staging of bladder cancers. EXPERIMENTAL DESIGN: Samples (54 total) of bladder tumor and corresponding normal bladder mucosa were analyzed for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16609023
DOI: 10.1158/1078-0432.ccr-05-2468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combination Analysis of Hypermethylated Wnt-Antagonist Family Genes as a Novel Epigenetic Biomarker Panel for Bladder Cancer DetectionPMID 16609023Read ↗

Wnt Antagonist Family Genes as Biomarkers for Diagnosis, Staging, and Prognosis of Renal Cell Carcinoma Using Tumor and Serum DNASemantic proximity Read ↗

Integrated genetic and epigenetic analysis of bladder cancer reveals an additive diagnostic value of FGFR3 mutations and hypermethylation events.Semantic proximity Read ↗

Epigenetic Inactivation of <i>SFRP</i> Genes and TP53 Alteration Act Jointly as Markers of Invasive Bladder CancerSemantic proximity Read ↗

Methylation of a Panel of MicroRNA Genes Is a Novel Biomarker for Detection of Bladder CancerSemantic proximity Read ↗

Promoter hypermethylation of HS3ST2, SEPTIN9 and SLIT2 combined with FGFR3 mutations as a sensitive/specific urinary assay for diagnosis and surveillance in patients with low or high-risk non-muscle-invasive bladder cancer.Semantic proximity Read ↗

DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patientsSemantic proximity Read ↗

Aberrant Promoter Methylation of Multiple Genes during Pathogenesis of Bladder CancerSemantic proximity Read ↗

Plasma DNA methylation of Wnt antagonists predicts recurrence of esophageal squamous cell carcinomaSemantic proximity Read ↗

DNA Methylation status of Wnt antagonist SFRP5 can predict the response to the EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer.Semantic proximity Read ↗

Promoter methylation of WNT inhibitory factor-1 may be associated with the pathogenesis of multiple human tumors.Semantic proximity Read ↗

Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer.Semantic proximity Read ↗

Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.