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Article

Plasma DNA methylation of Wnt antagonists predicts recurrence of esophageal squamous cell carcinoma

1 Jan 2011

Abstract excerpt

AIM: To detect the effects of plasma DNA methylation of Wnt antagonists/inhibitors on recurrence of esophageal squamous cell carcinoma (ESCC). METHODS: We used methylation-specific polymerase chain reaction to detect hypermethylation of the promoter of four Wnt antagonists/inhibitors (SFRP-1, WIF-1, DKK-3 and RUNX3) using DNA from the plasma of ESCC patients (n = 81) and analyzed the association between promoter...

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Share to Epigenetics and DNA Methylation
Share to Esophageal Cancer Research and Treatment
Share to Wnt/β-catenin signaling in development and cancer

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PMID: 22171134
DOI: 10.3748/wjg.v17.i44.4917

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