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Article

Generation of a constitutively active mutant of human GPR48/LGR4, a G-protein-coupled receptor.

[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Mar 2006

Gao Yun, Kitagawa Kyoko, Shimada Mai, Uchida Chiharu, Hattori Takayuki, Oda Toshiaki, Kitagawa Masatoshi

Abstract excerpt

GPR48, also known as leucine-rich repeat (LRR)-containing G-protein-coupled receptor 4 (LGR4), is a member of the G-protein-coupled receptor (GPCR) family of proteins. However, its biological functions remain unclear, since neither its ligand nor signal transduction pathway have been identified, and it is usually difficult to solve the function of such orphan receptors. The aim of this study was to generate a...

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PMID: 16607882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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