Article
fused-somites-like mutants exhibit defects in trunk vessel patterning.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2006
Shaw Kenna M, Castranova Daniel A, Pham Van N, Kamei Makoto, Kidd Kameha R, Lo Brigid D, Torres-Vasquez Jesus, Ruby Alexander, Weinstein Brant M
Abstract excerpt
We identified four mutants in two distinct loci exhibiting similar trunk vascular patterning defects in an F3 genetic screen for zebrafish vascular mutants. Initial vasculogenesis is not affected in these mutants, with proper specification and differentiation of endothelial cells. However, all four display severe defects in the growth and patterning of angiogenic vessels in the trunk, with ectopic branching and...
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