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Article

Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco.

Journal of clinical microbiology - 1 Apr 2006

Aga Roxanne S, Fair Elizabeth, Abernethy Neil F, Deriemer Kathryn, Paz E Antonio, Kawamura L Masae, Small Peter M, Kato-Maeda Midori

Abstract excerpt

We describe a microevolutionary event of a prevalent strain of Mycobacterium tuberculosis that caused two outbreaks in San Francisco. During the second outbreak, a direct variable repeat was lost. We discuss the mechanisms of this change and the implications of analyzing multiple genetic loci in this context.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16597893
DOI: 10.1128/JCM.44.4.1558-1560.2006
PMCID: PMC1448666

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Source receipt: pubmed, retrieved 7 Sept 2026.

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