Article
Inference about recombination from haplotype data: lower bounds and recombination hotspots.
Journal of computational biology : a journal of computational molecular cell biology - 1 Mar 2006
Bafna Vineet, Bansal Vikas
Abstract excerpt
Recombination is an important evolutionary mechanism responsible for creating the patterns of haplotype variation observable in human populations. Recently, there has been extensive research on understanding the fine-scale variation in recombination across the human genome using DNA polymorphism data. Historical recombination events leave signature patterns in haplotype data. A nonparametric approach for...
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