Article
Haplotypes histories as pathways of recombinations.
Bioinformatics (Oxford, England) - 12 Aug 2004
El-Mabrouk Nadia, Labuda Damian
Abstract excerpt
MOTIVATION: The diversity of a haplotype, represented as a string of polymorphic sites along a DNA sequence, increases exponentially with the number of sites if recombinations are taking place. Reconstructing the history of recombinations compared with that of the polymorphic sites is thus extremely difficult. However, in the human genome, because of the relatively simple pattern of haplotype diversity dominated...
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