Article
Functional nonsynonymous single nucleotide polymorphisms from the TGF-beta protein interaction network.
Physiological genomics - 24 Apr 2007
Savas Sevtap, Taylor Ian W, Wrana Jeff L, Ozcelik Hilmi
Abstract excerpt
Protein complexes mediated by protein-protein interactions are essential for many cellular functions. Transforming growth factor (TGF)-beta signaling involves a cascade of protein-protein interactions and malfunctioning of this pathway has been implicated in human diseases. Using an in silico app...
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