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Article

Functional nonsynonymous single nucleotide polymorphisms from the TGF-beta protein interaction network.

Physiological genomics - 24 Apr 2007

Savas Sevtap, Taylor Ian W, Wrana Jeff L, Ozcelik Hilmi

Abstract excerpt

Protein complexes mediated by protein-protein interactions are essential for many cellular functions. Transforming growth factor (TGF)-beta signaling involves a cascade of protein-protein interactions and malfunctioning of this pathway has been implicated in human diseases. Using an in silico approach, we analyzed the naturally occurring human genetic variations from the proteins involved in the TGF-beta...

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Identifiers

PMID: 17190851
DOI: 10.1152/physiolgenomics.00226.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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