Article
Relationship between interleukin 6 promoter polymorphism at position -174, IL-6 serum levels, and the risk of relapse/recurrence in polymyalgia rheumatica.
The Journal of rheumatology - 1 Apr 2006
Boiardi Luigi, Casali Bruno, Farnetti Enrico, Pipitone Nicolò, Nicoli Davide, Cantini Fabrizio, Macchioni Pierluigi, Bajocchi Gianluigi, Catanoso Maria Grazia, Pulsatelli Lia, Consonni Dario, Salvarani Carlo
Abstract excerpt
OBJECTIVE: To assess the role of -174 G/C promoter polymorphism of interleukin 6 (IL-6) in the susceptibility to polymyalgia rheumatica (PMR). We also investigated whether this polymorphism modulates the circulating level of IL-6 and the risk of relapse/recurrence in a series of patients with PMR...
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