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Article

Interleukin-6 gene -174 promoter polymorphism is associated with endothelial dysfunction but not with disease susceptibility in patients with rheumatoid arthritis.

Clinical and experimental rheumatology - 1 Jan 2000

Palomino-Morales R, Gonzalez-Juanatey C, Vazquez-Rodriguez T R, Miranda-Filloy J A, Llorca J, Martin J, Gonzalez-Gay M A

Abstract excerpt

OBJECTIVE: To determine whether the interleukin (IL)6 -174 gene polymorphism may influence the development of subclinical atherosclerosis manifested by the presence of endothelial dysfunction in RA patients. PATIENTS AND METHODS: 311 patients (228 [73.3%] women; 243 [78.1%] rheumatoid factor positive) who fulfilled the 1987 ACR classification criteria for RA seen at the Rheumatology outpatient clinic of Hospital...

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PMID: 20149313

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ACR

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