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Article

Role of the promoter polymorphism IL-6 -174G/C in dermatomyositis and systemic lupus erythematosus.

BioMed research international - 1 Jan 2013

Hristova Maria, Dourmishev Lyubomir, Kamenarska Zornitsa, Nikolova Svetla, Kaneva Radka, Vinkov Anton, Baleva Marta, Monova Daniela, Mitev Vanio

Abstract excerpt

The promoter polymorphism -174G/C within the interleukin-6 gene (IL-6) has been reported to have a functional importance through the modulation of IL-6 gene expression in vitro and in vivo. IL-6 is thought to play an important role in autoimmune diseases and the effect of its receptor inhibitor-tocilizumab-has been recently studied. The aim of this case-control study was to investigate the association between the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24106699
DOI: 10.1155/2013/315365
PMCID: PMC3784074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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