Article
HLA-C and KIR genes in hepatitis C virus infection.
Human immunology - 1 Nov 2005
Montes-Cano Marco Antonio, Caro-Oleas José Luis, Romero-Gómez Manuel, Diago Moisés, Andrade Raul, Carmona Isabel, Aguilar Reina José, Núñez-Roldán Antonio, González-Escribano María Francisca
Abstract excerpt
Natural killer (NK) cells are key components of the innate antiviral immune response. NK cell function is regulated by the interaction of major histocompatibility complex class I molecules with NK inhibitory receptors. The aim of this study was to investigate the role of the HLA-C/KIR pair in hepatitis C virus clearance in our population. A total of 196 hepatitis C virus-infected patients (65 resolved and 131...
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