Article
Genetic variation in the hepatic lipase gene and the risk of coronary heart disease among US diabetic men: potential interaction with obesity.
Diabetologia - 1 Jul 2006
Zhang C, Lopez-Ridaura R, Rimm E B, Li T, Hunter D J, Hu F B
Abstract excerpt
AIMS/HYPOTHESIS: The -514 C to T polymorphism of the hepatic lipase gene (LIPC) has been associated with lowered LIPC activity and elevated HDL-cholesterol concentrations. Previous findings on the association of this polymorphism with the risk of CHD are inconsistent. Moreover, data on this association among diabetic patients are limited. We investigated the association of the LIPC polymorphism with CHD risk...
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